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Out of 2,514 initially identified articles, 69 studies were ultimately included in the review based on relevance, study design, and therapeutic focus

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[9] [2] According to NICE guidance, patients with confirmed B12 deficiency and neurological involvement typically require more frequent initial dosing (alternate-day injections) until symptom improvement occurs

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Additional antioxidant Vitamin C stimulates collagen production and protects from free radical damage